Effect of conjugated linoleic acid on body fat in men with HIV receiving antiretroviral therapy

Not Applicable

Completed

• Conditions: HIV-associated lipodystrophy; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN31131566
• Lead Sponsor: King's College London

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2014-04-30
• Study Start: 2015-03-10
• Last Update Posted: 19 October 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 5

Inclusion Criteria

1. HIV positive
2. Age 18–55 years
3. On HAART
4. Waist circumference greater than >94 cm (37 inches) or ethnic-specific cutoff)
5. Overweight (body mass index > 25kg/m2)

Exclusion Criteria

1. Current AIDS-defining illness
2. Any acute/chronic condition that might affect the interpretation of the results or the participant's ability to follow protocol correctly
3. Fasting hypertriglyceridaemia (> 1.7 mmol/L)
4. Fasting hyperglycaemia (> 7mmol/L)
5. Male subjects on testosterone replacement therapy
6. Use of any medication designed to reduce weight/body fat
7. Participants following a diet (self-prescibed or practitioner-prescribed) to reduce weight/body fat
8. Use of fat-based supplements (e.g., fish oils) in the previous 3 months
9. Known hypersensitivity to the investigational products according to the participant and medical notes

Study & Design

• Study Type: Interventional
• Study Design: Not specified