Use of Lapis Judaicus to Dissolve Kidney Stones
- Conditions
- Kidney Calculi
- Interventions
- Drug: PlaceboDrug: Lapis Judaicus
- Registration Number
- NCT01443702
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
The investigators will investigate the safety and effectiveness of an Iranian traditional medicine regarding its ability to dissolve existing kidney stones. Calcium stone formers will be recruited for a 12 week trial. Each subject will receive Lapis judaicus or placebo in random order. End points are changes in urinary chemistries and stone burden by Ultra sonography / CT scan.
It will be used in proven calcium stone forming adults who are not pregnant. This phase is a double blind, randomized, placebo controlled Entry, first and 12 week 24 hour urine supersaturations, pH and sodium determinations will be collected. Entry and final stone quantification Ultra sonography / CT scan will be performed. End points will be changes in urine chemistry/supersaturation and stone quantitative stone volume.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Age 18 or over
- Mentally competent
- Medically effective birth control if fertile female
- History of calcium containing stone AND current quantifiable stone
- Able to comply with protocol
- Prisoner
- Pregnant
- CKD
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo - Lapis judaicus Lapis Judaicus -
- Primary Outcome Measures
Name Time Method Stone size after 12 weeks 8 weeks and 12 weeks 24 hour urine chemistries 24 hour urine supersaturation Stone quantification CT
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Motahhari Medical Center
🇮🇷Shiraz, Fars, Iran, Islamic Republic of