Effects of Aerobic Training Program On Liver Functions

Not Applicable

Completed

• Conditions: Liver Functions
• Interventions: Other: Aerobic training

• Registration Number: NCT05704608
• Lead Sponsor: King Saud University

Brief Summary

The liver plays a central role in energy exchange, protein synthesis as well as the elimination of waste products from the body. The optimal functioning of the liver is essential for athletic performance. It becomes necessary to maintain the enzymes of the liver at an optimal level so that liver cells can be protected from inflammation or damage. This paper investigated the effects of a twelve-week aerobic exercise program on the liver function of adult athletes. A total of thirty (30) healthy male athletes aged 21 to 24 were recruited for this study and kept in two equal groups. The control group was kept under rigorous supervision and did not participate in any special activities. The experiment group was well-versed in their assigned training program and solely performed the experimental procedure for twelve (12) weeks. Evaluation of all patients in both experimental and control groups was carried out before and after the treatment program by measuring the levels of (Alkaline phosphate, AST/SGOT, ALT/SGPT, Bilirubin Total/indirect/direct, Albumin, Globulin, and Total protein) respectively using standard methods by collecting blood samples, 5 mls each of baseline into lithium heparin containers for estimation of above biochemical parameters at the pathology laboratory accredited by National Accreditation Board for Testing and Calibration Laboratories accredited (NABL, India).

Detailed Description

Not available

Study Timeline

• Study Start: 2021-09-01
• Primary Completion: 2022-07-14
• Study Completion: 2022-11-30
• Status Verified: 2023-01
• Study First Submitted: 2023-01-19
• Study First Submitted QC: 2023-01-19
• Last Update Submitted: 2023-01-19
• Study First Posted: 2023-01-30
• Last Update Posted: 2023-01-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 30

Inclusion Criteria

• Male
• Age: 21-24 years
• Healthy
• Athletes

Exclusion Criteria

• history of severe illness,
• surgery, or damage to liver,
• fatty liver disease,
• cirrhosis,
• blood infections,
• neuromuscular illnesses,
• or the presence of any disorders such as fever, high blood pressure, high blood sugar

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experimental Group	Aerobic training	Aerobic training program was performed by participants.

Primary Outcome Measures

Name	Time	Method
Serum alanine transaminase/Serum Glutamic Pyruvic Transaminase (ALT/SGPT)	12 weeks.	Blood level of Serum ALT/SGPT was measured.
Albumin	12 weeks.	Blood level of Albumin was measured.
Bilirubin-Total	12 weeks.	Blood level of Bilirubin-Total was measured.
Serum aspartate aminotransferase/serum glutamic-oxaloacetic transaminase (AST/SGOT)	12 weeks.	Blood level of Serum AST/SGOT was measured.
Alkaline Phosphatase	12 weeks.	Blood level of Alkaline Phosphatase was measured.
Protein-Total	12 weeks.	Blood level of Protein-Total was measured.
Globulin	12 weeks.	Blood level of Globulin was measured.

Trial Locations

Locations (1)

King Saud University; 🇸🇦 Riyadh, Saudi Arabia