High Intensity Exercise Training in Type 2 Diabetes

Not Applicable

Completed

• Conditions: Type 2 Diabetes; Nutritional, Metabolic, Endocrine; Non-insulin-dependent diabetes mellitus

• Registration Number: ISRCTN78698481
• Lead Sponsor: ewcastle upon Tyne Hospitals NHS Foundation Trust (UK)

Brief Summary

2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/26265792 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/26350611 2019 results in: http://www.ncbi.nlm.nih.gov/pubmed/30541346 [added 15/03/2019]

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-01-23
• Study Completion: 2013-09-30
• Last Update Posted: 1 April 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

1. Aged between 30-70 years old
2. Diagnosed with Type 2 Diabetes which is metformin or diet controlled
3. BMI 25-35 kg/m2
4. Take part in no regular exercise

Exclusion Criteria

1. The absolute and relative contraindications to exercise testing as stated by the American Heart Association (Fletcher et al., 2001)
2. Taking insulin/Sulfonylurea/ TZD/ Beta-blockers
3. Contraindications for MRI scanning
4. Heart or kidney disease
5. Undergoing dietary change

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Glucose control (HbA1c)

Secondary Outcome Measures

Name	Time	Method
<br> 1. Liver fat<br> 2. Abdominal fat<br> 3. Cardiac function<br> 4. Resting and exercise metabolism (lipid oxidation)<br> 5. Cytokine production<br> 6. Insulin sensitivity<br> 7. Physical Activity<br>