Histidine-Rich Glycoprotein as a novel severity biomarker for sepsis: application to early treatment
Not Applicable
- Conditions
- Sepsis
- Registration Number
- JPRN-UMIN000030037
- Lead Sponsor
- Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
- Brief Summary
Although there was no time x survivors/non-survivors interaction in the time courses of HRG (P=0.34), the main effect of generalized linear mixed models was significant (P<0.001). In a univariate Cox proportional hazards model with each variable as a time-dependent covariate, higher HRG levels were significantly associated with a lower risk of mortality (hazard ratio, 0.85 [95%CI, 0.78-0.92]; P<0.001).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 201
Inclusion Criteria
Not provided
Exclusion Criteria
Pregnancy and Under 20 years old
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method