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Clinical Trials/NCT03966716
NCT03966716
Recruiting
N/A

HipSTHeR - a Registerbased Randomized Controlled Trial - Hip Screws or (Total) Hip Replacement for Undisplaced Femoral Neck Fractures in Elderly Patients.

Uppsala University25 sites in 1 country1,440 target enrollmentSeptember 16, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Femoral Neck Fractures
Sponsor
Uppsala University
Enrollment
1440
Locations
25
Primary Endpoint
Composite variable comprising reoperation rate and mortality
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

A registerbased RCT will investigate whether arthroplasty can decrease the reoperation rate compared to internal fixation for patients with an undisplaced femoral neck fracture (Garden I-II).

Detailed Description

The aim of this study is to determine whether the treatment of elderly patients with an undisplaced femoral neck fracture (uFNF) can be improved by decreasing reoperation rates through replacing the hip instead of trying to preserve it. Patients ≥75 years with an uFNF will be included and randomized within the Swedish Fracture Register (SFR) platform to internal fixation (screws/pins) or arthroplasty (choice of hemi or total is at the surgeon's discretion). The primary outcome will be a composite variable that combines two variables (reoperations and mortality) into a single variable.

Registry
clinicaltrials.gov
Start Date
September 16, 2019
End Date
September 1, 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Uppsala University
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Undisplaced (Garden I-II) femoral neck fracture (within 72h)
  • treated at participating unit
  • informed consent
  • amenable for both treatment options

Exclusion Criteria

  • no informed consent
  • pathological or stress fracture
  • peri-implant fracture

Outcomes

Primary Outcomes

Composite variable comprising reoperation rate and mortality

Time Frame: 1 to 2-year post-surgery

Both Death and mortality will be accounted for

Secondary Outcomes

  • Reoperation rate(2-year post-surgery)
  • Short-term Mortality(30 day mortality)
  • Long-term Mortality(2-year post-surgery)
  • Patient reported outcome: SMFA(1-year post surgery)

Study Sites (25)

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