Circadian Rhythm and performance

Phase 1

Completed

Conditions: healthy subjects

Registration Number: CTRI/2019/05/019236

Lead Sponsor: Centre for Physiotherapy and Rehabilitation Sciences

Brief Summary: 52 Healthy subjects will be recruited in this study on the basis of inclusion and exclusion criteria. i.e Morning Type and Evening Type on the basis of Questionnaire.

Morning type subjects will be randomly allocated into two groups, Group A (Morning type Morning Exercise) and Group B(Morning type Evening Exercise), Evening type subjects will be also randomly allocated in two groups, Group C (Evening type Morning Exercise ) and Group D (Evening type Evening exercise). All the four groups will be given 10 minutes of warm up and 3 minutes of cool down followed by high intensity interval training (4 x 4min intervals at 90-95% of maximum Heart Rate, each interval separated by 3 minutes at 70%, twice a week for 3 months),

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Male

Target Recruitment: 52

Inclusion Criteria

Male Healthy subjects Age: 18-30 years B.P 120/80 BMI: 18.5 â€“ 25 Morning type and Evening Type on the basis of Horne Ostberg Morningness â€“ Eveningness Questionnaire (1976), Subjects having basic understanding of English language and volunteering to participate in the study.

Exclusion Criteria

Receiving any Exercise training from last 3 months Any Musculoskeletal Injury Any Medical Condition Contraindicating physical exercise History or evidence of cardiovascular disease (history of angina, shortness of breath, uncontrolled hypertension).

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oxygen uptake: VO2max	12 weeks of exercised training protocol, Pre and post training data
Cardiac autonomic function: Heart rate recovery (HRR)	12 weeks of exercised training protocol, Pre and post training data
Heart rate variability (HRV)	12 weeks of exercised training protocol, Pre and post training data
Physical performance: Agility, Sprint and Vertical jump	12 weeks of exercised training protocol, Pre and post training data
Sleep Quality: Pittsburgh Sleep Quality Index (PSQI)	12 weeks of exercised training protocol, Pre and post training data
Biochemical Marker : Melatonin, Cortisol, testosterone, Oxidative stress (Catalase Superoxide Dismutase)	12 weeks of exercised training protocol, Pre and post training data

Secondary Outcome Measures

Name	Time	Method
NOT APPLICABLE	NOT APPLICABLE

Trial Locations

Locations (1): Centre for Physiotherapy and Rehablitation Sciences
🇮🇳
South, DELHI, India
Centre for Physiotherapy and Rehablitation Sciences
🇮🇳South, DELHI, India
Prof M Ejaz Hussain
Principal investigator
9899339816
ehusain@jmi.ac.in