The effects of an exercise intervention on pulmonary function, respiratory muscle strength, aerobic capacity and perception of breathlessness in a representative population of patients with Idiopathic Parkinson's Disease

Not Applicable

Completed

• Conditions: Topic: Dementias and Neurodegenerative Diseases Research Network; Subtopic: Parkinson?s Disease; Disease: Parkinson's disease; Nervous System Diseases; Parkinson disease

• Registration Number: ISRCTN13611537
• Lead Sponsor: orthumbria Healthcare NHS Foundation Trust (UK)

Brief Summary

2019 results in https://pubmed.ncbi.nlm.nih.gov/31606860/ (added 06/08/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-10-05
• Study Completion: 2015-05-08
• Last Update Posted: 17 August 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Idiopathic Parkinson?s Disease by the UK PD Society Brain Bank Criteria
2. Hoehn and Yahr Stage I-IV (I-III for RCT)
3. Ability to provide written informed consent
4. Aged 18 years or over

Exclusion Criteria

1. Other forms of Parkinsonism e.g. drug induced
2. Significant medical conditions which would preclude lung function testing
3. Significant medical conditions which would preclude exercise (RCT group)
4. Pregnancy
5. Recent diagnosis of a blood clot, deep vein thrombosis, pulmonary embolism or myocardial infarction
6. Unstable cardiac status, haemoptysis, pneumothorax, thoracic, abdominal or cerebral aneurysm
7. Recent eye, thoracic or abdominal surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Aerobic Capacity at baseline and end of 12 weeks

Secondary Outcome Measures

Name	Time	Method
Pulmonary Function at baseline and end of 12 weeks