Respiratory muscle training in patients with Parkinson's disease

Not Applicable

Completed

• Conditions: Parkinson's disease; Nervous System Diseases; Parkinson disease

• Registration Number: ISRCTN10301406
• Lead Sponsor: niversidad Andres Bello

Brief Summary

2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/29756459 results

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-11-27
• Study Start: 2018-01-16
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Participants of both genders with diagnosis of idiopathic Parkinson's disease (stage I-III Hoehn and Yahr scale) in the on dopaminergic” state were initially recruited in the study. Inclusion criteria were:
1. Diagnosis of idiopathic Parkinson's disease confirmed by a neurologist
2. Participants with the ability to understand and respond to the instructions given in the study
3. Unaltered dose and type of antiparkinsonian medication
4. Stable disease at the moment of inclusion in this study

Exclusion Criteria

1. Other concomitant neurological disease
2. Current smokers
3. Participants with a history of cardiovascular pathology, lung disease or the presence of respiratory symptoms such as cough, phlegm, wheezing or dyspnoea at the time of assessment
4. Participants with difficulties in maintaining a proper mouth seal or unable to avoid air leakage during pulmonary function testing

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Voluntary and reflex peak cough flow, measured using a pneumotachograph (MLT 1000; ADInstruments, Inc) coupled to a data acquisitions system (PowerLab 8/35, ADInstruments, Inc.), before and after 2 months of inspiratory or expiratory muscle training