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Clinical Trials/NCT01803217
NCT01803217
Completed
Not Applicable

AV-Hysteresis Versus Mode Switch to AAI (MVP) for the Avoidance of Unnecessary Right Ventricular Pacing

Deutsches Herzzentrum Muenchen3 sites in 1 country70 target enrollmentStarted: November 2007Last updated:
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ConditionsPacemaker Implantation for Sinus Node Disease

Overview

Phase
Not Applicable
Status
Completed
Sponsor
Deutsches Herzzentrum Muenchen
Enrollment
70
Locations
3
Primary Endpoint
Right ventricular pacing percentage
OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Overview

Brief Summary

Unnecessary right ventricular pacing has been shown to be detrimental in recipients of implantable pacemaker or defibrillators.

The ADVANTAGE study evaluates the efficacy of two pacemaker based algorithms (atrioventricular hysteresis function versus mode switch to atrial pacing) to reduce right ventricular pacing.

Detailed Description

Comparison of the effect of an atrioventricular hysteresis function with a mode switch to atrial pacing on the right ventricular pacing percentage in a multi-centre, prospective, randomized, single blinded, cross-over study.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Treatment
Masking
Single (Participant)

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Indication for the implantation of a dual-chamber pacemaker

Exclusion Criteria

  • •Persistent or permanent atrial tachyarrhythmias atrioventricular block 2nd or 3rd degree indication or the implantation of an defibrillator

Outcomes

Primary Outcomes

Right ventricular pacing percentage

Time Frame: 3 months

Secondary Outcomes

  • BNP levels(3 months)

Investigators

Sponsor
Deutsches Herzzentrum Muenchen
Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (3)

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