A randomised double blind placebo controlled trial of Fosphenytoin for prevention of seizures in children with acute non-traumatic encephalopathies

Completed

• Conditions: Acute non-traumatic encephalopathies; Signs and Symptoms; Seizure

• Registration Number: ISRCTN11862726
• Lead Sponsor: niversity College London (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-07-22
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

1. Children who are unable to localise a painful stimulus 30 minutes after a seizure or correction of hypoglycaemia
2. Written informed consent from the parents or guardian
3. Age nine months to 13 years

Exclusion Criteria

1. Children with a history of epilepsy, significant developmental delay, cerebral palsy, or sickle cell disease
2. Children who would have received phenytoin for treatment of seizures before recruitment
3. Evidence of head trauma

Study & Design

• Study Type: Interventional
• Study Design: Not specified