NCT06307158已完成不适用
Influence of Intraoperative Blood Salvage and Autotransfusion on Tumor Recurrence After Deceased Donor Liver Transplantation
Zhejiang University0 个研究点目标入组 998 人开始时间: 2015年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 998
- 主要终点
- Postoperative recurrence of liver cancer
研究概览
简要总结
The practice of intraoperative blood salvage and autotransfusion (IBSA) during deceased donor liver transplantation (DDLT) for hepatocellular carcinoma (HCC) can potentially reduce the need for allogeneic blood transfusion. However, implementing IBSA remains debatable due to concerns about its possible detrimental effects on oncologic recurrence. Hence, a nationwide multi-center study was conducted to investigate further the association between IBSA and post-transplant HCC recurrence, including a stratified subgroup analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult-to-adult deceased donor liver transplantation for hepatocellular carcinoma
排除标准
- •patients under 18 years of age
- •presence of extrahepatic metastasis
- •combined kidney transplantation
- •reduced-size or split liver transplantation
- •re-transplantation
结局指标
主要结局
Postoperative recurrence of liver cancer
时间窗: 2015.1.1-2020.12.31
The overall incidence of HCC recurrence (intrahepatic or extrahepatic) after LT.
次要结局
未报告次要终点
研究者
Xiao Xu
Professor
Zhejiang University
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