Recurrence ad Survival After Robotic Versus Laparoscopic Liver Resection in Very-early to Early (BCLC 0-A) Hepatocellular Carcinoma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 196
- 主要终点
- Overall survival
研究概览
简要总结
The objective of the study is to investigate the long-term outcomes of minimally invasive liver surgery (robotic vs laparoscopic) for hepatocellular carcinoma patients of stage BCLC 0-A. Data from two tertiary centers for liver surgery will be retrospectively reviewed. Patients will be divided in two cohorts (robot; laparoscopy). The primary endpoint will be recurrence-free and overall survival; secondary endpoints were incidence, pattern, and treatment of recurrences.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing robotic and laparoscopic resections
- •Histology-confirmed HCC of stage BCLC 0-A
- •Preserved liver function (Child score A-B)
- •Patients >18 years old
排除标准
- •Hand-assisted procedures
- •Non-elective surgery
- •Intraoperative switch to locoregional therapies (like radiofrequency or microwave ablation)
- •Non-histologically confirmed HCC
- •Mixed hepato-cholangiocarcinoma.
结局指标
主要结局
Overall survival
时间窗: From the date of liver resection until the date of death for any cause or the last follow-up available whichever came first, assessed up to 116 months. The Minimum follow-up accepted was of 3 months postoperatively.
Recurrence-free survival
时间窗: From the date of liver resection until the first documented HCC progression on follow-up imaging, assessed up to 116 months. The Minimum follow-up accepted was of 3 months postoperatively.
Recurrence was dated at the first HCC detection on follow-up imaging.
次要结局
未报告次要终点