Robotic Versus Laparoscopic Liver Resection for Hepatocellular Carcinoma
Completed
- Conditions
- Hepatocellular Carcinoma
- Registration Number
- NCT06496113
- Lead Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
- Brief Summary
The objective of the study is to investigate the long-term outcomes of minimally invasive liver surgery (robotic vs laparoscopic) for hepatocellular carcinoma patients of stage BCLC 0-A. Data from two tertiary centers for liver surgery will be retrospectively reviewed. Patients will be divided in two cohorts (robot; laparoscopy). The primary endpoint will be recurrence-free and overall survival; secondary endpoints were incidence, pattern, and treatment of recurrences.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 196
Inclusion Criteria
- Patients undergoing robotic and laparoscopic resections
- Histology-confirmed HCC of stage BCLC 0-A
- Preserved liver function (Child score A-B)
- Patients >18 years old
Exclusion Criteria
- Hand-assisted procedures
- Non-elective surgery
- Intraoperative switch to locoregional therapies (like radiofrequency or microwave ablation)
- Non-histologically confirmed HCC
- Mixed hepato-cholangiocarcinoma.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall survival From the date of liver resection until the date of death for any cause or the last follow-up available whichever came first, assessed up to 116 months. The Minimum follow-up accepted was of 3 months postoperatively. Recurrence-free survival From the date of liver resection until the first documented HCC progression on follow-up imaging, assessed up to 116 months. The Minimum follow-up accepted was of 3 months postoperatively. Recurrence was dated at the first HCC detection on follow-up imaging.
- Secondary Outcome Measures
Name Time Method