Food Addition and Hormone Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 23
- 试验地点
- 1
- 主要终点
- Electrogastrography (EGG) using Bipoac Systems EGG machine
研究概览
简要总结
The purpose of this exploratory study is to use Electrogastrography (EGG) to measure and compare the gastric myoelectrical activity between persons with food addiction (FA) and a control group. Additionally, this study will explore if differences exist between perceived hunger and satiety and hormone levels related to hunger and satiety in both groups. The comparison of the EGG readings and hormone levels is the next step in furthering our understanding of food addiction and how the physiology - not simply the symptomatology - of FA does or does not relate to weight management.
详细描述
The study will be conducted over 2 days and will consist of psychological assessments as well as EGG measurement (similar to EGG) and blood draws to examine hunger and satiety hormones.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participants will include men and women who identify with weight struggles related to disordered eating and a control sample of people who do not identify with weight issues or disordered eating. Must be able to read and write English
排除标准
- •Anyone with a chronic disease including type II diabetes, hypothyroidism, hypoparathyroidism, cardiovascular disease, cancer of any type
- •Anyone who is currently pregnant, or lactating
- •Medications that may influence or inhibit appetite, sensory functioning, or hormone signaling- e.g. antibiotics, anti-depressants, obesity medications
- •Report of medical condition or surgical intervention that affects swallowing ability
- •Allergy, aversion, or dislike to any of the meal replacements or snacks offered
- •Previous or current diagnosis of a psychiatric illness such as schizophrenia or any other psychotic disorder listed in the DSM-IV or DSM-5
- •Report of medical conditions that prohibits overnight fasting
结局指标
主要结局
Electrogastrography (EGG) using Bipoac Systems EGG machine
时间窗: the participant will be tested continuously for approximately 3 1/2 hours on 1 day, readings are collected on a PC
Skin electrode similar to EKG attached to abdomen and readings taken
次要结局
- Power of Food Scale(Day 1 5-10 minutes)
- Multidimensional Body-Self Relations Questionnaire - Appearance Scales(Day 1 5-10 minutes)
- Resting Metabolic Rate(10 min)
- Yale Food Addiction Scale 2.0(Day 1 5-10 minutes)
- Insulin(collected via IV catheter over approximately 3 1/2 hours on one day)
- The Center for Epidemiologic Studies Depression Scale(Day 1-5-10 minutes)
- GLP-1(collected via IV catheter over approximately 3 1/2 hours on one day)
- Automated Self-Administered (ASA) 24 Hour Recall(Day 1 5-10 minutes)
- Ghrelin(collected via IV catheter over approximately 3 1/2 hours on one day)
- Peptide YY(collected via IV catheter over approximately 3 1/2 hours on one day)
- Glucose(collected via IV catheter over approximately 3 1/2 hours on one day)
- GAD-7(Day 1 5-10 minutes)
- Trait and State Food Cravings Questionnaires(Day 1 5-10 minutes)
- Food Preoccupation Questionnaire(Day 1 5-10 minutes)
研究者
Cynthia Jefferson
Assistant Professor
Texas Tech University