A prospective imaging study of cruciate retaining and substituting knee replacement, in osteoarthritis and healthy aging: a randomised controlled trial

Canberra Hospital (Australia)0 个研究点目标入组 25 人开始时间: 2011年11月18日最近更新: 2019年12月10日

适应症

试验速览

•1. Total knee replacement group:
•1.1. Participant is awaiting total knee replacement
•1.2. The surgeon agrees that either a posterior-cruciate-retaining (PCR) or posterior stabilized (PS) knee is equally suitable for this participant
•1.3. Participant has osteoarthritis of the knee
•1.4. Participant is able to come back for 12 month follow up
•1.5. Participant is aged 40 ? 80 years
•2. Healthy age-matched control group:
•2.1. Participant is age-matched to a participant in total knee replacement (TKR) group
•2.2. Participant has no history of injury or osteoarthritis in either knee
•2.3. Participant has no pain in either knee
•3. Healthy aging group:
•3.1. Participant is aged 20-30, 40? 50, 60? 70, or 80+ years
•3.2. Participant has no history of injury or osteoarthritis in either knee
•3.3. Participant has no pain in either knee

•1. Total knee replacement group:
•1.1. Lateral compartment osteoarthritis only.
•1.2. Body mass index (BMI) > 38
•1.3. UCLA score of = 2
•1.4. Knee flexion < 90º
•1.5. Fixed flexion contracture of = 10º
•1.6. A psychosocial reason not be able to consent or complete the requirements of the study
•1.7. Metastatic disease
•1.8. Pathological fracture
•1.9. Revision knee replacement
•1.10. Poor understanding and is unable to provide informed consent
•1.11. Pregnant
•2. A healthy age-matched control group participant or a healthy aging group participant:
•2.1. Age under 20 years
•2.2. History of injury or osteoarthritis in either knee
•2.3. Pain in either knee
•2.4. Clinically reduced score on oxford knee score
•2.5. Clinical examination demonstrates pain, loss of range of motion, injury or osteoarthritis
•2.6. X- rays demonstrate injury or ostearthritis

发起方

Canberra Hospital (Australia)