NCT01807832Unknown不适用
The Use of Capsaicin Challenge for Diagnosis, Monitoring and Follow-up of Chronic Cough.
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 25
- 主要终点
- cough reflex hypersensitivity
研究概览
简要总结
The purpose of this study is to determine whether the capsaicin challenge can improve the diagnosis, treatment, monitoring and follow-up in patients with chronic cough.
详细描述
Capsaicin is administrated in incremental concentrations with two inhalations of normal saline solution. Patients are instructed to exhale to functional residual capacity and than to inhale through the mouthpiece for 1 second (single breath inhalation). The number of coughs in the first 10 seconds after each inhalation is counted. C2; the concentration of which the patient responded by 2 coughs, C5;the concentration of which the patient responded by 5 coughs. The challenge ends at C5.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with persisting cough for more than 3 months, without known respiratory or lung diseases
排除标准
- •Diagnosis of respiratory or lung diseases of any kind
结局指标
主要结局
cough reflex hypersensitivity
时间窗: 3 months
次要结局
未报告次要终点
研究者
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