NCT03659240已完成不适用
Prebiotic Effects of a Polyphenol-rich Food Product
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 2
- 主要终点
- Fecal microbial community composition and structure
研究概览
简要总结
The specific aim for this project will be to investigate a cranberry beverage as a means to restore balance in terms of the relative proportions of the various bacteria that inhabit the large intestine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI 27-35 kg/m2
- •High waist circumference (men >102 cm and women >88 cm)
排除标准
- •Cigarette smoking
- •Regular intensive exercise
- •Pregnancy or lactation
- •Chronic diarrhea, constipation, or other gastrointestinal complaint
- •Diabetes mellitus, autoimmune disease, or other chronic disease known to alter the gut microbiota
- •Use of medications that affect inflammation or the gut microbiota
- •Use of prebiotics, probiotics, synbiotics, vitamins, or other dietary supplements known to affect the gut microbiota
- •Aversion to cranberries
- •Food allergies
- •Lactose intolerance
- •Vegetarianism
结局指标
主要结局
Fecal microbial community composition and structure
时间窗: Changes in the fecal microbiota will be measured after a 20-day intervention period
We will investigate if specific bacterial taxa are stimulated by daily consumption of a cranberry beverage.
次要结局
未报告次要终点
研究者
Wendy S. White
Associate Professor
Iowa State University
研究点 (2)
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