Efficacy of Serratus Anterior Plane Block Using Bupivacaine/Magnesium Sulphate Versus Bupivacaine/Nalbuphine for Mastectomy: a Randomized Double Blinded Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- time to first analgesic requirements in minutes
研究概览
简要总结
Breast cancer is the main common cancer among females. . Inadequate control of pain may later develop into chronic pain syndrome (paraesthesias, phantom breast pain, and intercostobrachial neuralgia) in 25-40% of the patients .
详细描述
The aim of this study is to compare the efficacy of ultrasound-guided serratus anterior plane block with bupivacaine/ magnesium versus bupivacaine/ nalbuphine in breast cancer surgery.
Patients and methods nclusion criteria:
-ASA I and II female patients, age 25-60 undergoing breast cancer surgery
Exclusion criteria:
- Patient refusal
- Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy)
- Allergy to the drugs used in the study
- Chronic pain therapy,
- BMI more than 30 kg/m2
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 25 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •ASA I and II female patients, age 25-60 undergoing breast cancer surgery
排除标准
- •-Patient refusal
- •Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy)
- •Allergy to the drugs used in the study
- •Chronic pain therapy,
- •BMI more than 30 kg/m2
结局指标
主要结局
time to first analgesic requirements in minutes
时间窗: change from base line for 24 hours
time to first analgesic requirements in minutes by the patient
次要结局
未报告次要终点
研究者
doaa rashwan
Assistant profesor Doaa Rashwan
Beni-Suef University