Analgesic Efficiency of Superficial Serratus Plane Block for Modified Radical Mastectomy and Axillary Lymph Node Disection: Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Opioid Consumption
研究概览
简要总结
Breast cancer is the most common type of cancer in women. Mastectomy and axillary lymph node disection are commonly performed as part of the cancer management. This surgery can cause significant postoperative pain. The serratus plane block (SPB) has been described for analgesia of the hemithorax and reported for many cases such as thoracoscopy, shoulder arthroscopy, breast surgery and axillary lymph node dissections. Serratus plane block may be a viable alternative to current regional anaesthetic techniques such as thoracic paravertebral and central neuraxial blockade.
The aim of this study is to determine effectiveness of ultrasound guided superficial serratus plane block in patients undergoing modified radical mastectomy and axillary lymph node dissection surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologist's physiologic state I-III patients undergoing Modified Radical Mastectomy and Axillary Lymph Node Disection
排除标准
- •chronic pain, bleeding disorders, renal or hepatic insufficiency,patients on chronic non-steroidal anti-inflammatory medications
研究组 & 干预措施
Group Control
Ultrasound guided sham block with 2 ml saline subcutaneously
干预措施: Saline (Drug)
Group SPB
Ultrasound guided serratus plane block with 30 ml %0,25 bupivacaine
干预措施: Bupivacaine (Drug)
Group SPB
Ultrasound guided serratus plane block with 30 ml %0,25 bupivacaine
干预措施: Ultrasound (Device)
Group Control
Ultrasound guided sham block with 2 ml saline subcutaneously
干预措施: Ultrasound (Device)
结局指标
主要结局
Opioid Consumption
时间窗: First 24 hours total opioid consumption
First 24 hours total fentanyl consumption with patient controlled analgesia
次要结局
- Visual analog pain score(postoperative 24th hour)
研究者
Ahmet Murat Yayik
Principal Investigator
Ataturk University
