Metformin for gestational diabetes mellitus
Not Applicable
- Conditions
- Gestational diabetes mellitus.
- Registration Number
- IRCT201306057841N4
- Lead Sponsor
- Isfahan University of Medical Sciences, Vice-Chancellery for Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
1) 18-45 years aged; 2) pregnancy with a single fetus between 24 and 33 weeks of gestation; 3) current diagnosis of gestational diabetes mellitus according to the criteria of the Australasian Diabetes in Pregnancy Society (ADIPS); 4) no response to lifestyle modification (diet and exercise) after one week; 5) written informed consent. Exclusion criteria: 1) any contraindication for receiving metformin (renal or hepatic failure); 2) any history or documented diagnosis of diabetes prior to pregnancy; 3) history of sever drug reaction to the drugs in study; 4) any serious medical condition that may interfere with safe study participation
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hyperbilirubinemia. Timepoint: During the first two hours post partum. Method of measurement: Measuring blood bilirubin.;Pregnancy Induced Hypertention. Timepoint: During pregnancy every 2 weeks. Method of measurement: Measuring blood pressure.;Neonatal hypoglycemia. Timepoint: During the first two hours post partum. Method of measurement: Measuring blood sugar.;Preterm labor. Timepoint: During pregnancy every 2 weeks. Method of measurement: Evaluating symptoms of preterm labor by physical examination and history taking.;Birtth weight. Timepoint: During the first two hours post partum. Method of measurement: Measuring Neonatal weight.;Respiratory Distress Syndrom. Timepoint: During the first two hours post partum. Method of measurement: Physical examination.
- Secondary Outcome Measures
Name Time Method Control of maternal hyperglycemia. Timepoint: During Pregnancy every 2 weeks. Method of measurement: Measuring fasting blood sugar and blood sugar 2h pst prandial.