Good Prognosis Factors After Decompressive Craniectomy : a Ten-year Retrospective Study
- Conditions
- Decompressive CraniectomyBrain InjuriesTreatment Outcome
- Registration Number
- NCT04682951
- Lead Sponsor
- Central Hospital, Nancy, France
- Brief Summary
Decompressive craniectomy is a treatment of refractory intracranial hypertension after various etiologies : malignant ischemic stroke, traumatic brain injury, intraparenchymal hemorrhage, aneurysmal subarachnoid hemorrhage, cerebral venous thrombosis.
Initially considered as a lifesaving therapy, benefits in terms of survival were shown compared to medical treatment alone.
However, despite a better survival, morbidity and poor neurological outcome are frequent among survivors.
The objective of the study is to identify initial good neurological outcome factors after decompressive craniectomy in a large series of patients, in order to argue surgical and intensive care decisions, considering expected benefit and quality of life.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 544
- Patients undergoing a decompressive craniectomy from 06/11/2008 to 06/15/2018 in CHRU Nancy, France.
- Infectious ou malignant disease leading to decompressive craniectomy.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Good neurological outcome 6 months after surgery The neurological outcome is considered "good" when Glasgow Outcome Score extended (GOSE) assessed 6 months after decompressive craniectomy is between 5 and 8.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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Trial Locations
- Locations (1)
University Hospital of Nancy
🇫🇷Nancy, France
University Hospital of Nancy🇫🇷Nancy, France