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Clinical Trials/NCT04976335
NCT04976335
Recruiting
Not Applicable

Quantitative and Clinical Assessment of Flexor Tendon Gliding Following Application of a Bioresorbable Hydrogel: A Prospective, Randomized Study in Patients Undergoing Distal Radius Fracture Repair.

University of Colorado, Denver2 sites in 1 country50 target enrollmentSeptember 13, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Distal Radius Fracture
Sponsor
University of Colorado, Denver
Enrollment
50
Locations
2
Primary Endpoint
Range of Motion: Thumb Interphalangeal and Index Finger Distal Interphalangeal Joints
Status
Recruiting
Last Updated
7 months ago

Overview

Brief Summary

The investigators will be evaluating the use of versawrap in the setting of distal radius fractures by placing membrane between plate and flexor tendons. Investigators will then evaluate tendon gliding morphology and number of tendon ruptures

Registry
clinicaltrials.gov
Start Date
September 13, 2021
End Date
July 1, 2027
Last Updated
7 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Cognitively able to converse in English or in native language supported by a certified medical interpreter;
  • Diagnosed with a closed, distal radius fracture treated with open reduction and internal fixation using a volar distal radius plating system.

Exclusion Criteria

  • open injury;
  • concomitant injury to the contralateral wrist;
  • history of flexor tendon repair involving one or both hands or wrists;
  • use of a trans-carpal fixation device (bridge plate or external fixator) that would preclude wrist motion post-operatively;
  • concomitant fracture / injury to the thumb or index finger of one or both hands;
  • concomitant carpal tunnel release.

Outcomes

Primary Outcomes

Range of Motion: Thumb Interphalangeal and Index Finger Distal Interphalangeal Joints

Time Frame: 6 months

Standardized clinical examination (relative to wrist and digital positioning): active and passive range of motion for thumb interphalangeal and index finger distal interphalangeal joints.

Range of Motion: Thumb and Index Finger

Time Frame: 6 months

Standardized clinical examination (relative to wrist and digital positioning): active and passive composite digital range of motion for thumb and index fingers

Range of Motion: Wrist

Time Frame: 6 months

Standardized clinical examination (relative to wrist and digital positioning): active and passive wrist range of motion.

Ultrasound Assessment of Flexor Pollicis Longus and Index Finger Flexor Digitorum Profundus Tendon Excursion

Time Frame: 6 Months

Tendons in the volar forearm will be directly visualized with ultrasound. The distance the tendons are able to travel (excursion) within the forearm will be reported.

Secondary Outcomes

  • Complications(6 months)
  • Patient-Rated Wrist Evaluation (PRWE)(6 Months)
  • Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH)(6 Months)
  • Visual Analog Scale (VAS) pain scores(6 Months)
  • Subjective Reporting Specific to Tendon Function(6 Months)
  • Key Pinch(6 Months)
  • Three-Jaw Pinch(6 Months)
  • Grip Strength(6 Months)
  • Soong Classification(6 Months)
  • Ultrasound Assessment of Flexor Pollicis Longus and Index Finger Flexor Digitorum Profundus Tendon Morphology(6 Months)

Study Sites (2)

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