Physical Therapy After Endometriosis Excision

Not Applicable

Not yet recruiting

• Conditions: Endometriosis; Surgery

• Registration Number: NCT07127783
• Lead Sponsor: Oregon Health and Science University

Brief Summary

This is a randomized controlled pilot study comparing a home pelvic floor physical therapy program to routine post-operative care for patients undergoing endometriosis excisional surgery without hysterectomy. Quality of life and endometriosis symptoms will be compared following the recovery period.

Detailed Description

This is a randomized controlled pilot study conducted at a single institution comparing a home pelvic floor physical therapy program to routine post-operative care for patients undergoing endometriosis excisional surgery without hysterectomy. Patients will be recruited from a referral gynecological surgery group specializing in the diagnosis and treatment of pelvic pain and endometriosis. The goal is to assess the role of the active recovery program on quality of life and on pain and endometriosis symptoms.

Subjects will be randomized to routine post-operative care or to a home physical therapy program, in which they will receive written instruct ions and videos of exercises to complete immediately after surgery. The home exercise program was developed by the Department of Urogynecology in conjunction with pelvic floor physical therapists, and includes videos created by the education communications division. Quality of life, pain score, and endometriosis symptoms will be assessed at their pre-operative appointment, and at 6 and 12 weeks postoperatively.

Study Timeline

• Status Verified: 2025-08
• Study Start: 2025-08-01
• Study First Submitted: 2025-08-11
• Study First Submitted QC: 2025-08-11
• Last Update Submitted: 2025-08-11
• Study First Posted: 2025-08-17
• Last Update Posted: 2025-08-17
• Primary Completion: 2026-03
• Study Completion: 2026-03-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

• Premenopausal
• English speaking
• Undergoing endometriosis excision surgery without hysterectomy at Legacy Health with subspecialty-trained surgeons specializing in endometriosis care
• History of chronic pelvic pain (defined as >= 6 months of pain in the anatomic pelvis)
• Diagnosis of high tone pelvic floor dysfunction on examiniation
• Have access to reliable email and phone for study-related communication

Exclusion Criteria

• Non-English speaking
• Unable to consent
• Unable to sustain 30 minutes of moderate activity at baseline
• Uses a mobility assistive device at baseline
• Chronic opioid use
• No histologic diagnosis of endometriosis on surgical pathology
• Need for additional pelvic rest (>2 weeks) postoperatively
• Pregnancy or planning to pursue pregnancy or undergo fertility treatments within 12 weeks postoperatively

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Short Form Survey (SF-36)	Collected immediately following surgery, 6 weeks following surgery, and 12 weeks following surgery	The Short Form Survey (SF-36) is a 36-item survey regarding general health and pain and its impact on quality of life including physical activities, work, social activities, and emotional well-being over the last four weeks. Scores range from 0 to 100 with a higher score representing a more favorable health state.
Pelvic Floor Impact Questionnaire (PFIQ)	Collected immediately following surgery and 12 weeks following surgery	The Pelvic Floor Impact Questionnaire (PFIQ) asks about how bladder, bowel, and pelvic symptoms affect the ability to do physical activities as well as their impact on emotional well-being over the last 3 months. Scores range from 0 to 300 with a lower score representing a lesser impact on quality of life.

Secondary Outcome Measures

Name	Time	Method
Pain Scores	Collected at baseline, 6 weeks following surgery, and 12 weeks following surgery.	Pain measured using a Visual Analog Scale (VAS). This scale asks patients to rate their pelvic pain and dyspareunia over the last 4 weeks. Responses are on a scale from 0 to 10, with 10 being the worst pain.
Endometriosis Health Profile (EHP-5)	Collected at baseline, 6 weeks following surgery, and 12 weeks following surgery.	The Endometriosis Health Profile (EHP-5) is a 5-item questionnaire asking about the perception of endometriosis symptoms on physical ability, emotional well-being, mood, social isolation, and appearance over the last four weeks. Scores range from 0 to 100 where 0 indicates the best health status.

Trial Locations

Locations (1)

Oregon Health & Science University; 🇺🇸 Portland, Oregon, United States