NCT00448396已完成1 期
An Open Label Phase I Study to Evaluate the Effects of Patupilone on the Pharmacokinetics and Pharmacodynamics of Warfarin in Patients With Advanced Malignancies
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 17
- 主要终点
- To evaluate the effects of patupilone on the pharmacokinetics of warfarin in patients with advanced malignancies.
研究概览
简要总结
To evaluate the effects of patupilone on the pharmacokinetics of warfarin in patients with advanced malignancies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Patupilone
Experimental
干预措施: Patupilone (Drug)
结局指标
主要结局
To evaluate the effects of patupilone on the pharmacokinetics of warfarin in patients with advanced malignancies.
次要结局
- To evaluate the effects of patupilone on the pharmacodynamics of warfarin in patients with advanced malignancies.
- Safety and tolerability of patupilone when administered concomitantly with warfarin in patients with advanced malignancies will be assessed by AE's, SAE's and safety labs.
研究者
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