A COG Soft Tissue Sarcoma Diagnosis, Biology and Banking Protocol
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 247
- 主要终点
- Collection of clinical data on patients who are not being treated on a COG therapeutic study
研究概览
简要总结
The purpose of this study is to collect and store tumor tissue, blood, and bone marrow samples from patients with soft tissue sarcoma that will be tested in the laboratory. Collecting and storing samples of tumor tissue, blood, and bone marrow from patients to test in the laboratory may help the study of cancer.
详细描述
PRIMARY OBJECTIVES:
I. Collect human tumor tissue and other biological specimens (blood, serum, and bone marrow) from patients with rhabdomyosarcoma or non-rhabdomyosarcoma soft tissue sarcoma diagnosed and/or treated at a Children's Oncology Group (COG) member institution.
II. Provide a repository for storage of tissue and other biological specimens collected by COG investigators from these patients.
III. Make these specimens available for approved projects by laboratory-based investigators.
IV. Collect clinical data on these patients who are not being treated on a COG therapeutic study.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- — 至 50 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically or cytologically confirmed diagnosis of 1 of the following:
- •Rhabdomyosarcoma
- •Non-rhabdomyosarcoma soft tissue sarcoma
- •Desmoid fibromatosis
- •Desmoplastic round cell tumors
- •Undifferentiated embryonal sarcoma of the liver
- •Unclassified soft tissue sarcoma that is too undifferentiated to be placed in a specific pathologic category in the WHO classification (often called ?undifferentiated soft tissue sarcoma? or ?soft tissue sarcoma NOS?)
- •Other soft tissue neoplasms, excluding benign tumors
- •Must have pathological specimens of tumor-containing tissue or bone marrow (beyond that needed by the institution for diagnosis) available for study
- •No malignant rhabdoid tumor, Ewing sarcoma/primitive neuroectodermal tumor, or osteogenic sarcoma of bone
- •No osteogenic sarcoma
排除标准
- 未提供
结局指标
主要结局
Collection of clinical data on patients who are not being treated on a COG therapeutic study
时间窗: Up to 10 years
Collection of human tumor tissue and other biological specimens (blood, serum, and bone marrow) from patients with rhabdomyosarcoma or non-rhabdomyosarcoma soft tissue sarcoma
时间窗: Up to 10 years
次要结局
未报告次要终点