The optimal effect site concentration of target-controlled infusion with propofol in gynecological surgery

• Conditions: The optimal effect-site propofol concentration (Ce) during maintenance and in each stage of anesthesia in Thai female patients undergoing gynecological surgery; Effect site concentration; propofol TCI; Eleveld model

• Registration Number: TCTR20220207005
• Lead Sponsor: Maharaj Nakorn Chiang Mai Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-02-07
• Study Completion: 2022-07-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: Female
• Target Recruitment: 54

Inclusion Criteria

1. Age 18-60 years, 2. ASA classification 1-3

Exclusion Criteria

1) Abnormal liver function
2) Uncontrolled cardiovascular diseases
3) Inability to understand and communication
4) Obesity (BMI> 30)
5) Pregnancy
6) Drug abuse
7) Allergy to medications used in the protocol
8) Risk difficult intubation
9) Surgery duration > 6 hours

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
effect-site concentration at maintenance of anesthesia target-controlled infusion

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A