Comparison of Karpasa Moola & Patra Churna in White discharge

Phase 2/3

Completed

Registration Number: CTRI/2022/09/045608

Lead Sponsor: Government Ayurved College and Hospital Vadodara

Brief Summary: Clinical study has obtained Institutional EthicsCommittee clearance (GAC/VAD/IEC/71/2021, Dated 15Sept. 2021) and registeredat Clinical Trial Registry of India, ICMR, New Delhi, vide CTRI/2022/09/045608 (Registeredon 16/09/2022). Study type was randomized single blind clinical trial. Selectedpatient was randomly derived divided into two groups [18 in group A (*Karpasa**Moola* *Churna*) - & 18 in group B (*Karpasa* *Patra* *Churna*)]out of which total 18 patients in group A and 15 patients in group B hadcompleted the treatment dose (3gm â€“ 2 time per day before meal) schedule ofinternal application. In Group A highly significant result was found in *Yonigata**Shwetasrava*, *Yonikandu*, *Katishoola*, *Daurbalya* and *Angamarda*while significant result was found in *Yonipichchhillata* and *Adhodarashoola*.In Group A highly significant result was found in *Yonigata* *Shwetasrava*,*Yonikandu* and *Angamarda* while significant result was found in *Katishoola*,*Daurbalya* and *Adhodarashoola*. When comparing Group A with Group Bsignificant result were found in *Yonigata* *Shwetasrava* and *Yonikandu*.The variations observed in hematological parameters before and after treatmentwere statistically non-significant. There is only one patient was observed forcomplete remission from Group A, percentage of marked improvement in Group Aand Group B 44.44% and 40% respectively, Moderate improvement percentage ingroup A i.e. 50% and 40% in group B, 20% of mild improvement from Group. Nochanges result was not found in any group.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Female

Target Recruitment: 30

Inclusion Criteria

1 Age between 18 to 45 years of female patients 2 Shwetasrava(Yonigata) 3 Yonikandu 4 Katishoola.

Exclusion Criteria

1 Per-vaginal white discharge due to Malignant condition,Cervicitis, cervical erosion & PID 2 Infection like STD 3 Planning for pregnancy 4 Pregnancy 5 Puerperium 6 Disease like DM etc.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Complete remission of the major symptoms i.e. Yonigata Shwetasrava (White vaginal discharge) and Yonikandu (vaginal itching)	4 Weeks

Secondary Outcome Measures

Name	Time	Method
Relief in other symptoms like Katishoola (Low backache), Yonigata alpavedana (Mild vaginal pain), Daurbalya (Weakness)	4 Weeks

Trial Locations

Locations (1): Government Ayurved Hospital Vadodara
🇮🇳
Vadodara, GUJARAT, India
Government Ayurved Hospital Vadodara
🇮🇳Vadodara, GUJARAT, India
Dr Mira C Khodifad
Principal investigator
7046780569
meerakhodifad125@gmail.com