Comparing the analgesic effect of intrathecal Sufentanil with intravenous Acetaminophen in combination with low-dose Ketamine on labor pai

Phase 2

• Conditions: Analgesia in Labour.; Maternal complications arising from the administration of a general or local anaesthetic, analgesic or other sedation during labour and delivery

• Registration Number: IRCT2017082935979N1
• Lead Sponsor: Vice chancellor for research in Qazvin university of medical sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

Inclusion criteria are as follows:
oPregnant women who are candidates for natural delivery and are in the active phase (Cervical dilatation of 5-3 cm);
oPregnant women with no history of physical and psychological illness or biochemical abnormalities (ASA I class);
oPregnant women who have written and complete consent for the study.
Exclusion criteria are as follows:
oDissatisfaction pregnant women;
oMother's preeclampsia and eclampsia;
oInsulin-dependent diabetes;
oMother drug abuse history;
oUsing any analgesic method before entering the study;
oHistory of liver disease;
oHistory or presence of bleeding disorder and coagulation disorders in the mother;
ousing anticoagulant drugs;
oHistory of mental illness or using antidepressants or anticonvulsants;
oAny contraindication for spinal anesthesia;
oHistory of allergic reactions or intolerant to the drugs studied (Sufentanil, acetaminophen and ketamine);
oAny significant or severe systemic disease that limits usual and natural activities (such as kidney disease that require dialysis, class 2 heart failure and ….).

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: During the intervention. Method of measurement: VAS.

Secondary Outcome Measures

Name	Time	Method
Age. Timepoint: During Of Intervention. Method of measurement: Year.;Weight. Timepoint: During Of Intervention. Method of measurement: kilogram.;First stage of Labour. Timepoint: During Of Intervention. Method of measurement: Minute.;Neonate APGAR. Timepoint: During Of Intervention. Method of measurement: 1to10.;Blood Pressure. Timepoint: During Of Intervention. Method of measurement: Mm Hg.;Ephedrine Amount. Timepoint: During Of Intervention. Method of measurement: mg.;Heart Beat. Timepoint: During Of Intervention. Method of measurement: Beat per minute.;Nausea and Vomiting. Timepoint: During Of Intervention. Method of measurement: Yes/NO.;Amount of Natural delivery. Timepoint: During Of Intervention. Method of measurement: Number.;Petedin Amount. Timepoint: During Of Intervention. Method of measurement: mg.;Second Stage Of Labour. Timepoint: During Of Intervention. Method of measurement: Minute.