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Clinical Trials/NCT07579780
NCT07579780RecruitingNot Applicable

Superior Hypogastric Plexus Block for Early Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Trial

Sixth Affiliated Hospital, Sun Yat-sen University1 site in 1 country170 target enrollmentStarted: December 15, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Sponsor
Enrollment
170
Locations
1

Study Overview

Brief Summary

This trial seeks to assess the efficacy of a superior hypogastric plexus block for early quality of recovery after laparoscopic colorectal cancer surgery.

Detailed Description

This study is a single-center, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy of superior hypogastric plexus block (SHPB) in improving the quality of postoperative recovery in patients undergoing laparoscopic colorectal cancer surgery. A total of 170 eligible patients will be enrolled and randomly assigned in a 1:1 ratio to receive either SHPB or placebo block. The primary outcome is the 15-item Quality of Recovery (QoR-15) score at 24 hours postoperatively. Secondary outcomes include visceral pain numerical rating scale (NRS) scores at rest and during movement within 48 hours postoperatively, morphine consumption, time to first flatus, incidence of postoperative ileus, length of hospital stay, and inflammatory cytokine levels (such as interleukin-6 and C-reactive protein). This study aims to elucidate the evidence-based medical position of SHP block within the Enhanced Recovery After Surgery (ERAS) strategy for laparoscopic colorectal cancer surgery.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Able to provide informed consent.
  • Undergoing elective laparoscopic radical resection for colorectal cancer.
  • American Society of Anesthesiologists Physical Status (ASA) class I-III.

Exclusion Criteria

  • Allergy to block medication (s).
  • Coagulation dysfunction.
  • Local or systemic infection.
  • Unable to cooperate with the completion of the study protocol.

Investigators

Sponsor
Sixth Affiliated Hospital, Sun Yat-sen University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Xiangcai Ruan, MD, PhD

Professor

Sixth Affiliated Hospital, Sun Yat-sen University

Study Sites (1)

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