The cardiac electrophysiological effects and the investigation on the incidence of post-operative cognitive dysfunction (POCD) on using of Remimazolam. (a retrospective-test) - The cardiac electrophysiological effects and the investigation on the incidence of post-operative cognitive dysfunction (POCD) on using of Remimazolam. (a retrospective-test)

Kindai university faculty of medicine0 sites100 target enrollmentNovember 9, 2021

Overview

No summary available.

Registry

who.int

Start Date

November 9, 2021

End Date

March 31, 2022

Last Updated

2 years ago

Study Type

Observational

Sex

All

Sponsor

•1\) Cases using "excluded drugs" 2\) Patients under the age of 20 at the time of obtaining the comprehensive consent form 3\) Patients with AST (GOT) or ALT (GPT) of 100 IU / L or higher in general preoperative laboratory tests 4\) Patients with Child\-Pugh classification B or C 5\) Patients with serum creatinine of 2\.0 mg / dL or higher in general preoperative laboratory tests 6\) Patients who have been using benzodiazepines for a long time 7\) When there is a possibility that EEG and BIS values cannot be measured properly due to organic abnormalities in the brain or other surgical procedures. 8\) Patients who underwent epidural anesthesia / spinal anesthesia (Because it may be affected by local anesthesia or premedication) 9\) Patients with cardiac pacemakers and ICDs (because they are not suitable for electrocardiogram analysis) 10\) The research subject has declared his intention to refuse by oral writing. 11\) Other patients judged to be inappropriate by the principal investigator