Evaluation Of Effect of Axial Length on Cup-To-Disc Ratio Among Non- Glaucomatous Hypertensive Patients

Active, not recruiting

• Conditions: Hypertensive Complication

• Registration Number: NCT06913478
• Lead Sponsor: Superior University

Brief Summary

This observational cross-sectional study aims to compare the effect of axial length on the cup-to-disc ratio in non-glaucomatous hypertensive patients. Data will be collected from Khursheed Begum Eye Hospital and LRBT Hospital, with a sample size of 104 participants. A purposive sampling technique will be used.

Detailed Description

Patients aged 18-70 years with systemic hypertension for at least one year and normal intraocular pressure will be included. Exclusion criteria include glaucoma, high myopia, hyperopia, ocular surgery, trauma, and optic nerve diseases. Axial length will be measured using optical biometry or A-scan ultrasonography, while the cup-to-disc ratio will be assessed through fundus examination using a slit lamp biomicroscope with a +90D lens or optical coherence tomography (OCT). Data will be meticulously documented, including patient demographics and medical history. The study will be completed within six months after approval, ensuring accurate and standardized measurements for reliable results.

Study Timeline

• Status Verified: 2025-03
• Study Start: 2025-03-20
• Study First Submitted: 2025-03-29
• Study First Submitted QC: 2025-03-29
• Last Update Submitted: 2025-03-29
• Study First Posted: 2025-04-06
• Last Update Posted: 2025-04-06
• Primary Completion: 2025-06-20
• Study Completion: 2026-02-20

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 94

Inclusion Criteria

• Male and female patients diagnosed with systemic hypertension for at least 1 year.
• Age between 18-70 years.
• Normal intraocular pressure (IOP<-21mmhg)
• Axial length between 21mm and 26mm (to exclude extreme refractive errors)

Exclusion Criteria

• History of glaucoma or ocular hypertension.
• High myopia (<-6.00 D) or hyperopia (>+6.00D).
• History of ocular surgery, trauma, or retinal diseases.
• Any optic nerve diseases.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Axial length measured by biometry and CD ratio by slitlamp	12 Months	The axial length, measured in millimeters, is defined as the distance from the anterior surface of the cornea to the retinal pigment epithelium. The axial length can be measured using either ultrasound biometry (accomplished via direct contact or immersion) or optical biometry

Trial Locations

Locations (1)

Alshifa eye clinic Ali Pur chattha; 🇵🇰 Gujrānwāla, Punjab, Pakistan