Myocardial Infarction in the Perioperative Setting, a Swedish Multi Center Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 400,742
- 试验地点
- 1
- 主要终点
- Acute Myocardial Infarction
研究概览
简要总结
Acute myocardial infarction (AMI) is a significant complication following non-cardiac surgery. The investigators sought to evaluate incidence of perioperative AMI, its preoperative and intraoperative risk factors and the outcomes after this complication.
详细描述
Background:
In Sweden, over 800 000 patients undergo surgery each year. Worldwide, the number of surgical procedures yearly is over 310 million. Surgical care is an essential part of the advancement in treating disease, associated with increased life expectancy and improved quality of life. However, as surgical volume continues to grow, the number of patients who suffer postoperative complications will also increase.
More specifically the project aims to answer the following questions:
- How common is perioperative acute myocardial infarction following non-cardiac surgery?
- What are the preoperative and intraoperative risk factors for peroperative AMI?
- Does perioperative AMI affect mortality and morbidity, Length of stay and days at home?
- Is the risk of AMI affected by the type of hospital, region or calendar year of surgery?
Orbit - surgical planning system:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults (≥18 years), male and female
- •Undergoing elective or non-elective inpatient noncardiac surgery
排除标准
- •Cardiac surgery
结局指标
主要结局
Acute Myocardial Infarction
时间窗: Within 30days of the index surgery
AMI, as detected in the postoperative phase in the electronic medical records or in the Swedeheart registry
次要结局
- Mortality(Within 30days of the index surgery and at later predefined time points: 60, 90, 180 and 365 days after the index surgery)
研究者
Max Bell
MD, PhD, Associate Professor, Senior Lecturer
Karolinska University Hospital