Comparative evaluation of different CMR pulse-sequences with respect to their practicability and diagnostic performance in diagnosing the inflamed myocardium in patients with acute myocardial infarction based on the detection of macrophages in the infarcted myocardium using Resovist® and FerahemeTM
- Conditions
- Patients with acute myocardial infarctionMedDRA version: 9.1Level: LLTClassification code 10000891Term: Acute myocardial infarction
- Registration Number
- EUCTR2008-008936-10-DE
- Lead Sponsor
- Division of Cardiology, Robert-Bosch-Krankenhaus
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- acute STEMI or NSTEMI (minimally 2d to maximally 7d before the scheduled CMR imaging)
- age >18 yrs
- coronary artery disease
- myocardial infarction detected by contrast-imaging with gadolinium-based compounds
- ability to give written consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
- contraindications to magnetic resonance imaging
- contraindications to Resovist/Feraheme
- asthma / allergic predisposition
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method