Comparison of the effect of hypertonic and normal saline on the success of resuscitation in patients with septic shock
Phase 3
Recruiting
- Conditions
- Septic shock.R57.2
- Registration Number
- IRCT20111212008384N7
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
Patients with septic shock,
Age between 80-18 years
Exclusion Criteria
Patient dissatisfaction,
Patients with incurable disseminated malignancy,
Patients with hypernatremia,
Patients receiving colloidal solutions such as albumin, etc.
Any volume-limiting restrictions such as irreversible heart failure
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemodynamic parameters (heart rate, mean arterial pressure, systolic blood pressure, diastolic blood pressure, central venous pressure). Timepoint: At the beginning of the patient's study and in the first, second and third hours of the intervention. Method of measurement: Hemodynamic parameters by monitoring device andCentral venous pressure rulers are measured.
- Secondary Outcome Measures
Name Time Method 1- Gasometric parameters 2- Optical nerve diameter. Timepoint: At the beginning of the patient's study and in the first, second and third hours of the intervention (optic nerve diameter at the beginning and the third hour of the intervention), they are measured, recorded and compared. Method of measurement: Gasometer and sonography device.