Efficacy of Aloe vera toothpaste during active periodontal treatment: A clinical study
- Conditions
- While professional dental treatments are mandatory for advance periodontitis, maintaining proper oral hygiene can significantly contribute to preventing disease progression. Some herbal toothpastes and natural plant components may have some beneficial properties. . A toothpaste containing salt and Aloe vera may have adjunctive influence to non-surgical periodontal treatment.Aloe vera, Herbal product, Toothpaste, Periodontitis, Periodontal treatment
- Registration Number
- TCTR20240516001
- Lead Sponsor
- the National Science and Technology Development Agency under the Ministry of Science and Technology, Thailand.
- Brief Summary
Aloe vera toothpaste significantly decreased gingival bleeding, probing depth, and clinical attachment level in periodontitis patients during active periodontal treatment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 54
The subjects were required to
1. Have at least 4 permanent teeth with periodontal pocket depth greater than 4 mm along with radiographic alveolar bone destruction
2. Have full mouth plaque score more than 40 percent
3. Exhibit bleeding on probing more than 30 percent
4. Be in the age range of 20 to 70 years
5. Provide informed consent
The participants who
1. Had been diagnosed as dental plaque induced gingivitis or nonplaque induced gingival lesions
2. Had nonsurgical periodontal treatment in the preceding 12 months,
3. Had orthodontic treatment within 12 weeks
4. Had periodontal surgery in the preceding 12 weeks
5. Had ongoing treatment with antimicrobials and/or anti-inflammatory medication
6. Had been pregnancy or lactation
7. Had been smoking or alcohol abuse
8. Had a history of an allergic reaction to the toothpastes
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method gingival inflammation 3 months bleeding gon probing
- Secondary Outcome Measures
Name Time Method probing depth reduction 3 months probing depth