Day-night rhythmicity in patients with a nonfunctioning pituitary macroadenoma; a prospective study

Completed

• Conditions: non - hormone secreting benign tumor of the pituitary gland; nonproducing pituitary macroadenoma; 10021112

• Registration Number: NL-OMON42817
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Diagnosed nonfunctioning pituitary macroadenoma, not yet received surgery

Exclusion Criteria

age <18 years or > 70 years old
mentally incompentent

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. Registration of day-night rhythmicity using actigraphy and sleep diaries<br /><br>2. Questionnaires assessing sleep quality and quality of life<br /><br>3. Clinical parameters from standard patient care, e.g. laboratory results, MRI<br /><br>of pituitary region, and visual field assessment<br /><br>4. Melatonin in saliva<br /><br>5. Visual Evoked Potentials</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>none</p><br>