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An Open-label Trial to Determine Increased Red Blood Cell Production in Subjects With Anemia of Chronic Disease

Phase 3
Conditions
Anemia of Chronic Disease
Interventions
Drug: ESS (medical food/drug)
Registration Number
NCT01846689
Lead Sponsor
Targeted Medical Pharma
Brief Summary

The objective of this study is to measure the change in blood values after the administration of an amino acid based erythropoietin stimulating system.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
30
Inclusion Criteria
  1. M/F patients 18 years old and over, non-pregnant/lactating
  2. Hemoglobin < 10 female,<11 male
  3. Ferritin > upper limit of normal for lab indicative of chronic anemia
  4. Anemia of chronic disease
  5. Crt. < 3.0
Exclusion Criteria
  1. Currently taking other amino acid formulations.
  2. Pregnant or unwilling to use adequate birth control for the duration of the study.
  3. Excessive alcohol or illicit drug use.
  4. Unwilling or unable to sign informed consent.
  5. Myocardial infarction within the last 6 months.
  6. Patients ever having taken or currently taking an erythropoietin medication.
  7. Iron deficiency (add criteria).
  8. On dialysis.
  9. Malignancy other than non-melanoma skin cancer within the last 5 years. If has such malignancy, must have documentation of no recurrence for at least 5 years.
  10. Liver cirrhosis (add criteria).

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
ESSESS (medical food/drug)Prescription medical food erythropoietin stimulating system
Primary Outcome Measures
NameTimeMethod
Hemoglogin/Hematocrit28 Days
Secondary Outcome Measures
NameTimeMethod
Red blood cell count28 Days
Reticulocyte count28 days
IGF-128 days

Trial Locations

Locations (1)

Targeted Medical Pharma

🇺🇸

Los Angeles, California, United States

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