Comparison of Recovery Profile and Patient Hemodynamics after sedation with ketamine with either Dexmedetomidine or Propofol in patients undergoing Endoscopic Retrograde Cholangio Pancreatography
- Conditions
- Health Condition 1: - Health Condition 2: K839- Disease of biliary tract, unspecified
- Registration Number
- CTRI/2022/01/039451
- Lead Sponsor
- Dr Aruna Bharti
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
18 to 65 year old ASA I and II patients who have consented to participate in the study
Nonconsenting patients.
Patients allergic to egg, allergy to study drugs assessed by prior history
Baseline SpO2 <94% on room air
BMI >35kg/m2 due to altered drug metabolism and clearance
Pregnant and lactating patients.
Psychiatric disorders (schizophrenia) as Ketamine is contraindicated in such patients
Heart blocks, arrhythmias, Patient with pacemakers
Patients with increased intracranial pressure, eg-patients with space occupying lesion in brain, h/o Cerebrovascular Accident in the previous one year
Severe liver dysfunction (Child Pugh class C).
ASA III and IV are not considered as they have liver dysfunction causing significant side effects of dexmedetomidine due to reduced clearance that requires dose adjustments and increases recovery time.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method comparing the recovery profile between the groups after the procedureTimepoint: awake and recovery time are assessed at the end of the procedure
- Secondary Outcome Measures
Name Time Method