ISRCTN84968882已完成4 期
A single-centre randomised controlled trial of propofol cardioplegia on blood and myocardial biomarkers of stress and injury in patients having isolated coronary artery bypass grafting (CABG) or aortic valve replacement (AVR) using cardiopulmonary bypass (CPB)
niversity Hospitals Bristol NHS Foundation Trust (UK)0 个研究点目标入组 96 人开始时间: 2009年11月11日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 96
研究概览
简要总结
2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/25004932
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Current inclusion criteria as of 01/02/2011:
- •1. Male or female
- •2. Age =18 to =80 years
- •3. Having elective or urgent CABG or AVR with CPB at the BHI
- •4. Able to give full informed consent for the study
- •Previous inclusion criteria:
- •1. Male or female
- •2. Aged greater than or equal to 16 years to less than or equal to 80 years
- •3. Having elective or urgent CABG or AVR with CPB at the Bristol Heart Institute (BHI)
- •4. Able to give full informed consent for the study
排除标准
- •Current inclusion criteria as of 01/02/2011:
- •1. Previous cardiac surgery
- •2. Combined CABG and AVR
- •3. Emergency or salvage operation
- •4. Chronic renal failure requiring dialysis
- •5. Current congestive heart failure
- •6. Left ventricular ejection fraction less than 30% (i.e. poor LV function)
- •7. Allergy to peanuts, eggs, egg products, soybeans or soy products
- •8. Already participating in another clinical (interventional) study
- •Previous inclusion criteria:
- •2. Concomitant CABG/AVR procedure
研究者
相似试验
已完成
不适用
Effectiveness of preventive support groups for children (aged 8-12) of mentally ill or addicted parentsMental health problems in children at riskMental and Behavioural DisordersBehavioural and emotional disorders with onset usually occurring in childhood and adolescenceISRCTN48032451The Netherlands Organisation for Health Research and Development [ZonMw] (Netherlands)228
已完成
不适用
A randomised, controlled, factorial pilot study investigating omacor and/or fluvastatin in patients with chronic hepatitis C who have not responded to standard combination anti-viral therapyChronic viral hepatitisISRCTN48248159ewcastle upon Tyne Hospitals NHS Foundation Trust (UK)72
已完成
不适用
A randomised controlled trial comparing conventional, active and passive self-ligating orthodontic bracket systemsISRCTN51381850Record Provided by the NHSTCT Register - 2007 Update - Department of Health100
已完成
不适用
The improvement effect of probiotics using tablet containing Lactobacillus salivarius WB21 on bad breathOral malodorSigns and SymptomsHalitosisISRCTN74332440Fukuoka Dental College (Japan)26
已完成
不适用
Immunomonitoring by virus-specific T-cells and evaluation as a prognostic marker for virus-induced diseases after solid organ transplantatioPaediatric kidney transplantationSurgerySurgical operation and other surgical proceduresISRCTN89806912Medical School of Hannover (MHH) (Germany)64