ISRCTN03624752已完成2 期
A single centre randomised interventional treatment trial of botulinum toxin-A versus placebo in the improvement of active function in upper limb disability of stroke survivors
niversity College London (UK)0 个研究点目标入组 28 人开始时间: 2010年5月12日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 28
研究概览
简要总结
2014 results in: http://discovery.ucl.ac.uk/id/eprint/1459867 2020 results in https://pubmed.ncbi.nlm.nih.gov/31747825/ (added 23/04/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Clinically confirmed diagnosis of stroke
- •2. More than 1 month post-stroke
- •3. An Ashworth score of 2 or more
- •4. The ability to pick up a mug and move it to another position (so that participants are able to use any improvement in hand control in functional reach and grasp tasks)
- •5. Aged 18 years and over (no max), both male and female participants
排除标准
- •1. Orthopaedic impairments affecting the hemiplegic upper limb or spine
- •2. Additional neurological impairment not related to stroke
- •3. Shoulder or wrist pain (greater than 3 on a 0 - 10 visual analogue scale) whilst performing the experimental tasks
- •4. Severe cognitive impairment preventing informed consent and/or the ability to follow task instructions
- •5. Anti-coagulation with an international normalised ratio (INR) of greater than 2
研究者
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