Impact of Fluid Resuscitation on Venous Congestion in Cardiac Critically-ill Patients

Not yet recruiting

• Conditions: Cardiac and Aortic Surgery; Cardiac Anaesthesia; Fluid Resuscitation; Venous Congestion

• Registration Number: NCT07183397
• Lead Sponsor: Medical University of Vienna

Brief Summary

The objective of this study is to assess how fluid resuscitation, in the context of fluid responsiveness, affects the incidence and progression of systemic venous congestion in critically ill cardiac patients. Additionally, the study aims to evaluate the impact on clinical outcomes, with a particular focus on acute kidney dysfunction. This assessment will utilize the VExUS score in conjunction with comprehensive bedside echocardiographic evaluations.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-09
• Study First Submitted: 2025-09-14
• Study First Submitted QC: 2025-09-14
• Last Update Submitted: 2025-09-14
• Study Start: 2025-09-15
• Study First Posted: 2025-09-19
• Last Update Posted: 2025-09-19
• Primary Completion: 2027-09
• Study Completion: 2027-12-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

• Age above 18 years
• Admission to cardiac intensive care unit

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Venous congestion	7 days	Venous congestion as assessed by the VExUS score at ICU admission, and on each of the first seven postoperative days.
Acute kidney injury	Twenty-eight days	Acute kidney injury (AKI), defined through the KDIGO criteria, within seven and twenty-eight days of ICU admission.