Clinical study of rhubarb combined with probiotics to improve cytokine storm in patients with ARDS
Phase 1
Recruiting
- Conditions
- Acute respiratory distress syndrome
- Registration Number
- ITMCTR2100004252
- Lead Sponsor
- Affiliated Hospital of Jiangsu University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1. Aged 18-70 years;
2. Patients admitted to ICU;
3. The diagnosis meets the ARDS criteria and the mechanical ventilation time is greater than or equal to 48 hours;
4. Patients or their family members sign informed consent, cooperate with the investigation and comply with the patients.
Exclusion Criteria
1. Patients who died within 72 hours after tracheal intubation;
2. Pregnant women;
3. Patients with immunodeficiency/injury;
4. Patients with gastrointestinal obstruction or bleeding;
5. Diabetic.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inflammatory factor levels;
- Secondary Outcome Measures
Name Time Method ymphocyte count;Intestinal flora composition;28-day mortality;Short-chain fatty acid content in serum and stool;Neutrophil count;temperature;Procalcitonin;White blood cell count;