NCT00693836UnknownNot Applicable
Resource for the Study of Lung Cancer Epidemiology in North Trent
Cancer Research Centre at Weston Park Hospital1 site in 1 country2,000 target enrollmentStarted: January 2006Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 2,000
- Locations
- 1
- Primary Endpoint
- Establishment of a resource bank of high quality genomic and plasma DNA and tumor and serum samples
Study Overview
Brief Summary
RATIONALE: Gathering information about genetic and environmental factors from patients with lung cancer and their partners and first-degree relatives may help doctors learn more about the disease.
PURPOSE: This clinical trial is looking at the patterns, causes, and control of disease in patients with lung cancer in the North Trent (England) region.
Detailed Description
OBJECTIVES:
Primary
- To establish a resource bank of high quality genomic and plasma DNA and tumor and serum samples linked to clinical data obtained from detailed family history and lifestyle questionnaires from patients with lung cancer and from their partners and first-degree relatives for genetic epidemiology studies of lung cancer.
Secondary
- To study single nucleotide polymorphisms for candidate lung cancer susceptibility genes in genomic DNA samples from patients with lung cancer and from their partners and first-degree relatives.
- To study genetic changes of lung cancer in plasma DNA samples from patients with lung cancer and from their partners and first-degree relatives.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Establishment of a resource bank of high quality genomic and plasma DNA and tumor and serum samples
Secondary Outcomes
- Genetic changes of lung cancer in plasma DNA samples
- Analysis of single nucleotide polymorphisms for candidate lung cancer susceptibility genes in genomic DNA samples
Investigators
Study Sites (1)
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