Risk Communication in African American Smokers

Not Applicable

Completed

• Conditions: Lung Cancer
• Interventions: Behavioral: HRHA; Behavioral: LRLA; Behavioral: HRLA; Behavioral: LRHA

• Registration Number: NCT04084561
• Lead Sponsor: Temple University

Brief Summary

The study aims to understand the effects of learning about one's genetic risk for lung cancer that is specific to their ancestry. Participants will be given hypothetical personalized genetic risk results and ask to think about how they might respond to such information if they actually received such results.

Detailed Description

The study aims to understand the effects of learning about one's genetic risk for lung cancer that is specific to their ancestry. Smokers will be randomized to receive hypothetical information about their genetic status and consider how they think they would respond if such results were actually presented to them. They will be randomly assigned to receive one of four sets of hypothetical genetic results: 1) High risk of lung cancer and high genetic African ancestry, 2) High risk of lung cancer and low genetic African ancestry, 3) Low risk of lung cancer and high genetic African ancestry, or 4) Low risk of lung cancer and low genetic African ancestry. After being given this hypothetical information, participants will complete brief questionnaires assessing perceived risk of lung cancer, worry about cancer, psychological distress, and motivation to quit smoking.

Study Timeline

• Study Start: 2018-09-01
• Study First Submitted: 2019-09-06
• Study First Submitted QC: 2019-09-06
• Study First Posted: 2019-09-10
• Primary Completion: 2022-04-01
• Study Completion: 2022-04-01
• Results First Submitted: 2023-05-03
• Status Verified: 2023-11
• Results First Submitted QC: 2023-11-27
• Last Update Submitted: 2023-11-27
• Results First Posted: 2023-12-18
• Last Update Posted: 2023-12-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 166

Inclusion Criteria

• 18 years of age minimum
• Self-report African American
• Report smoking at least 100 lifetime cigarettes

Exclusion Criteria

• Report history of cancer

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
HRHA	HRHA	High Risk, High Ancestry
LRLA	LRLA	Low Risk, Low Ancestry
HRLA	HRLA	High Risk, Low Ancestry
LRHA	LRHA	Low Risk, High Ancestry

Primary Outcome Measures

Name	Time	Method
Motivation to Quit Smoking	1 minute after intervention	use self report 7 item (condition options) MTSS (Motivation to Stop Smoking) Scale with yes/no option to determine the quitting intention condition; range of scale : 1-7, with higher score means higher motivation to quit smoking

Trial Locations

Locations (2)

Hunter College; 🇺🇸 New York, New York, United States

Fox Chase Cancer Center; 🇺🇸 Philadelphia, Pennsylvania, United States