Ultrasound Guided Supraclavicular Brachial Plexus Block, Volume Comparison of Local Anaesthetics and Diaphragmatic Motility.

Phase 4

• Conditions: Sucessful Block With Less Hemidiaphragmatic Paresis in Distal Upper Arm Fracture
• Interventions: Procedure: ultra sound guided supraclavicular brachial plexus block

• Registration Number: NCT03476694
• Lead Sponsor: B.P. Koirala Institute of Health Sciences

Brief Summary

Brachial plexus block as done by landmark technique use large volume of local anaesthetics (at least 30-40 ml), leading to higher incidence of phrenic nerve involvement and diaphragmatic dysfunction. With use of ultrasound dose of local anaesthetic can be reduced. Volume as low as 20 ml when use by ultrasound guidance has shown to provide successful block with no hemidiaphragmatic palsy when compared with nerve stimulation technique. But no study has compared the different volumes of drug on success rate and diaphragmatic motility.So in this study , the investigators want to compare the incidence of hemidiaphragm paralysis and success of block with different volumes of local anaesthetic , so that the lowest effective dose with higher safety profile can be determined.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-03-18
• Study First Submitted QC: 2018-03-18
• Study First Posted: 2018-03-26
• Status Verified: 2018-06
• Last Update Submitted: 2018-06-28
• Last Update Posted: 2018-06-29
• Study Start: 2018-07-01
• Primary Completion: 2019-02-01
• Study Completion: 2019-02-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
25ml of 0.75% Ropivacine	ultra sound guided supraclavicular brachial plexus block	-
20ml of 0.75% Ropivacine	ultra sound guided supraclavicular brachial plexus block	-

Primary Outcome Measures

Name	Time	Method
hemidiaphragmatic paralysis	within 30 minutes after sucessfull blocade	grading of hemidiaphragmatic paralysis as, complete ,partial and no hemidiaphragmatic paralysis as reduction of diaphragmatic excursion greater than 75%, 25-75%, less than 25% respectively after sucessful blocade.

Secondary Outcome Measures

Name	Time	Method
sucessful blocade	within 30 minutes of block	ultrasound guided supraclavicular brachial plexus block using ropivacine and observing the complete block.

Trial Locations

Locations (1)

B P Koirala Institute of Health science (BPKIHS); 🇳🇵 Dharān Bāzār, Koshi Zone, Nepal