Comparision of Misoprostol versus sequential administration of Mifepristone and Misoprostol in Medical Termination of Pregnancy
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 210
- 试验地点
- 1
- 主要终点
- complete expulsion of product of conception within 24hrs of the first dose of misoprostol
研究概览
简要总结
abortion is defined as termination of pregnancy before fetus is viable. There are medical as well as surgical methods. medical methods include misoprostol , mifepristone, gemeprost etc. Surgical methods include menstrual regulation, vaccum aspiration, dilation and curratage and hysterotomy or hysterectomy. But surgical methods have complications like hemorrhage, perforation and infection. Medical abortion has potential advantage over the surgical complications.
sequential administration of mifepristone followed by misoprostol has shown superior to the misoprostol alone. Hence present study is undertaken to evaluate the efficacy of mifepristone followed by misoprostol versus misoprostol alone.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 21.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •All cases those will fulfil indication of Medical Termination of Pregnancy, as per guidelines of MTP Act of 1971.
排除标准
- •Scarred uterus Ectopic pregnancy Grand multipara Contraindications to misoprostol and mifepristone.
结局指标
主要结局
complete expulsion of product of conception within 24hrs of the first dose of misoprostol
时间窗: complete expulsion of product of conception within 24hrs of the first dose of misoprostol
次要结局
- induction abortion interval will be measured from the time of administration of first dose of misoprostol to the time of complete abortion. The need of analgesics and volume of blood loss will be estimated clinically.(after 24 hours induction)