Clinical Characteristics and Etiology of Infectious Optic Neuritis in Thailand

Completed

• Conditions: Demographic data, clinical features, laboratory investigation, imaging study, clinical outcomes, etiology and associated factors to poor visual outcome of patients with infectious optic neuritis.; infectious optic neuritis, parainfectious optic neuritis, demographic, clinical, investigation, treatment, imaging, clinical outcome, etiology, risk factor

• Registration Number: TCTR20211115001
• Lead Sponsor: Chulalongkorn University

Brief Summary

Our study proposed the epidemiology, demographic data, clinical characteristics, investigation data, treatment and prognosis of ION in Thailand. There were some clinical characteristics pattern recognized in some causative pathogens. Prognosis was variable but seemed to be excellent in TION and worse on FION. However, because of its rarity, our data was still small and further study needs to be carried out to identify more specific clinical entity of each specific pathogen of ION.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-15
• Study Completion: 2022-04-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Infectious or para-infectious optic neuritis patients who were diagnosed at the King Chulalongkorn Memorial Hospital from 2007 to 2019.

Exclusion Criteria

- The patient whose the clinical data at the initial presentation cannot be acquired.
- The patient whose follow up duration was less than one year except for the patient who had complete resolution of disease before 1 year or who was dead by a complication of the infection or treatment of optic neuritis.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual Acuity of right eye at presentation, 1 month, 3 months, 6 months and 12 months after presentation Reviewing electronic medical record,Visual Acuity of left eye at presentation, 1 month, 3 months, 6 months and 12 months after presentation Reviewing electronic medical record

Secondary Outcome Measures

Name	Time	Method
Gender Date of admission Reviewing electronic medical record,Date of Birth Date of admission Reviewing electronic medical record,Diabetes Mellitus (Underlying) Date of admission Reviewing electronic medical record,HIV status Date of admission Reviewing electronic medical record,Other underlying disease Date of admission Reviewing electronic medical record