MedPath

The Effect of Periradial Injection of Papaverine Versus Nitroglycerine on Radial Artery Diameter

Early Phase 1
Completed
Conditions
Radial Artery Injury Prevetion
Interventions
Registration Number
NCT04030663
Lead Sponsor
Kasr El Aini Hospital
Brief Summary

Compare the effect of periradial injection of papaverine versus nitroglycerine on radial artery diamter before cannulation of it in cardiac surgery.

Detailed Description

we want in this study to facilitate radial artery canulation and decrease the number of attemps of puncture which may lead to disappearance of the pulse.

The aim of this study is to compare the effect of adding papaverine to local anesthetic xylocaine versus adding nitroglycerine to it on the diameter and palpability of radial artery and if perioperative spasm will decrease significantly with one of these methods.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
90
Inclusion Criteria
  • Patients who will be included in the study are those scheduled for elective cardiac surgery who are hemodynamically stable.
Exclusion Criteria
  • Any patient with negative modified Allen test, atrioventricular block, glaucoma, altered liver function, unstable hemodynamics, emergency surgeries, and peripheral vascular disease.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
xlyocainexlyocaine-
nitroglycerinenitroglycerine-
papaverinepapaverine-
Primary Outcome Measures
NameTimeMethod
diameter of radial artery20 minutes

after periradial injection of one of the drugs we will feel the radial artery pulse and record if there is a change in the palpatory score and mesure the diameter of the radial artery by ultrasound in cardiac surgery patients

Secondary Outcome Measures
NameTimeMethod
spasm of radial artery24 hours

detect if there is postoperative spasm of radial artery

Trial Locations

Locations (1)

Faculty of Medicine

🇪🇬

Cairo, Benisuef, Egypt

© Copyright 2025. All Rights Reserved by MedPath