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临床试验/CTRI/2022/07/044093
CTRI/2022/07/044093已完成Phase 3 4

Effect of samana snehapana with sahacharadi taila in comparison to dhanwantaram taila in the management of osteoarthritis of knee joint

Government Ayurveda college panchakarma hospital poojappura Thiruvananthapuram1 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2022年7月21日最近更新:

试验速览

阶段
Phase 3 4
状态
已完成
发起方
入组人数
32
试验地点
1
主要终点
WOMAC Osteoarthritis index

研究概览

简要总结

Osteoarthritis of knee joint is a common progressive multifactorial joint disease and is characterized by chronic pain and functional disability. OA is the second most common rheumatologic problem of 22% to 39% in India. OA is common in women than men, but the prevalence increase dramatically with age. In Ayurveda OA knee may be well considered as Sandhigata vata a type of VataVyadhi affecting the sandhi, explained by all the acharayas. As vata is predominantly vitiated, Snehanam is one of the effective treatment to treat vitiated vata. Among the snehana therapy, Samana snehapana could be very effective treatment modality. Sandhigata vata / OA knee is a condition where cartilage in the knee degenerates results in bone rubbing together and creating stiffness, pain and impaired movements. Sahacaradi taila, in Astanga hridaya, Astanga sangraha which is mentioned in Vatavyadhi chikitsa and it is very effective in adha – kaya vata rogas. The objectives of this study is to compare the effect of samana snehapana with Sahacaradi tailaand Dhanwantaram taila in the management of OA knee. The study is comparative clinical trial with control group. Participants of both sex, aged 40 – 60 years registered in OPD and IPD of Government Ayurveda college Panchakarma Hospital, Trivandrum satisfying the inclusion criteria will be subjected to consecutive sampling and the total of 32 participants will be selected for the study. The data will be collected through observation, clinical case proforma and X-ray. After collecting baseline data, detailed history and examination will be done using clinical case proforma. A total of 32 participants will be selected for the study. They will be subjected to consecutive sampling, divided in to 2 groups (Group A and Group B). In Group A Sahacaradi taila as samana sneha pana will be given for 14 days and Group B, Dhanwantaram taila assamana snehapana will be given for 14 days. Both the groups will be assessed before and after the intervention on 0th day, 6th day, after treatment on 20th day, followup on 35th day and 65thday. The result will be analyzed statistically by using Descriptive and „Mann Whitney U Test‟.Keywords : Osteoarthritis, Sandhigata vata, Samana snehapana, Sahacaradi taila, Dhanwantaram taila.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
40.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • participants of both sex among age group 40-60 years of age.
  • Diagnosed cases of OA knee on the basis of clinical signs and symptoms and according to Kellgren and Lawrence system of classification of OA knee up to grade
  • Participants who are indicated for snehapana 4) Participants with informed consent.

排除标准

  • Inflammatory arthritis 2) Congenital abnormalities 3) Participants with knee replacement implants 4) Participants with uncontrolled diabetes and hypertension, severe liver and renal disorder, malignancy.

结局指标

主要结局

WOMAC Osteoarthritis index

时间窗: 6th day, after treatment 20th day,follow up 35th day, 65th day

TUG Test scoring of timed up and go test

时间窗: 6th day, after treatment 20th day,follow up 35th day, 65th day

次要结局

未报告次要终点

研究者

发起方
Government Ayurveda college panchakarma hospital poojappura Thiruvananthapuram
申办方类型
Government medical college

研究点 (1)

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