Diet and the Aging Brain
Phase 3
Completed
- Conditions
- Healthy
- Registration Number
- NCT00463255
- Lead Sponsor
- University Hospital Muenster
- Brief Summary
We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.
- Detailed Description
The age-related degradation of cognitive functions even to the point of neurodegenerative disorders such as alzheimer's disease are a growing public-health concern with potentially devastating effects.
Refering to animal data and empirical studies, a healthy diet rich in unsaturated fatty acids and low in calories should improve cognitive functions such as learning and memory. To test this hypothesis, we study general brain functions in healthy elderly subjects (50-80 years old) during a short term diet.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
- healthy subjects
- 50-80 years old
- moderate to heavy weight
- must be able to change diet at home
Exclusion Criteria
- diabetes
- younger than 50 years
- BMI < 23
- already participating in other studys
- MMSE > 26
- eating disorders
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method implicit visual-motor learning of a finger sequence of the hand.
- Secondary Outcome Measures
Name Time Method implicit learning of an artificial language several plasma levels related to cognitive functions
Trial Locations
- Locations (1)
University Hospital Muenster, Department of Neurology
🇩🇪Muenster, NRW, Germany